HRT Shortage UK

Track hormone replacement therapy supply issues across the UK

Updated 8 February 2026 from official DHSC & NHS data
30
Active shortages
24
High severity
HRT shortages have been a recurring issue in the UK, particularly affecting estrogen patches like Estradot. These shortages impact women managing menopause symptoms and those on HRT for other medical reasons. Multiple Serious Shortage Protocols are currently active.

Current Active Shortages

Estradot® 25 microgram patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradot® 25 microgram patches (PDF:218KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 03 April 2025

Estradot® 100 microgram patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradot® 100 microgram patches (PDF:215KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 December 2024

Estradot® 75 microgram patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradot® 75 microgram patches (PDF:219KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 December 2024

Estradot® 50 microgram patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradot® 50 microgram patches (PDF:219KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 December 2024

Estradot® 100mcg patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradot® 100mcg patches (PDF:218KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 21 Aug 2023

Utrogestan® 100mg capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Utrogestan® 100mg capsules (PDF:193KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 May 2023

Estradot® 75mcg patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradot® 75mcg patches (PDF:216KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 13 Apr 2023

Progynova® TS 100mcg patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Progynova® TS 100mcg patches (PDF:217KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 28 Mar 2023

Estradot® 100mcg patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradot® 100mcg patches (PDF:205KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 25 Jan 2023

Estradot® 50mcg patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradot® 50mcg patches (PDF:205KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 25 Jan 2023

Estraderm MX® 75mcg patches substitution

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estraderm MX® 75mcg patches substitution (PDF:214KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 15 Nov 2022

Estraderm MX® 50mcg patches substitution

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estraderm MX® 50mcg patches substitution (PDF:214KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 15 Nov 2022

Estraderm MX® 100mcg patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estraderm MX® 100mcg patches (PDF:214KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 08 Sep 2022

Estraderm MX® 25mcg patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estraderm MX® 25mcg patches (PDF:213KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 08 Sep 2022

Estradiol (Sandrena®) 0.5mg and 1mg gel sachets substitution and restriction

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradiol (Sandrena®) 0.5mg and 1mg gel sachets substitution and restriction (PDF:751KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 May 2022

Estradiol (Sandrena®) 0.5mg and 1mg gel sachets substitution

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradiol (Sandrena®) 0.5mg and 1mg gel sachets substitution (PDF:751KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 May 2022

Estradiol (Sandrena®) 0.5mg and 1mg gel sachets restriction

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradiol (Sandrena®) 0.5mg and 1mg gel sachets restriction (PDF:600KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 May 2022

Estradiol (Lenzetto®)1.53mg/dose transdermal spray substitution and restriction

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradiol (Lenzetto®)1.53mg/dose transdermal spray substitution and restriction (PDF:749KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 May 2022

Estradiol (Lenzetto®)1.53mg/dose transdermal spray substitution

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradiol (Lenzetto®)1.53mg/dose transdermal spray substitution (PDF:748KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 May 2022

Estradiol (Lenzetto®)1.53mg/dose transdermal spray restriction

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradiol (Lenzetto®)1.53mg/dose transdermal spray restriction (PDF:601KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 May 2022

Estradiol (Oestrogel® Pump-Pack 0.06% gel) 0.06% gel (750microgram per actuation) substitution and restriction

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradiol (Oestrogel® Pump-Pack 0.06% gel) 0.06% gel (750microgram per actuation) substitution and restriction (PDF:751KB). Pharmacists may supply alternatives wit...

Expected resolution: 19 May 2022

Estradiol (Oestrogel® Pump-Pack 0.06% gel) 0.06% gel (750microgram per actuation) substitution

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradiol (Oestrogel® Pump-Pack 0.06% gel) 0.06% gel (750microgram per actuation) substitution (PDF:750KB). Pharmacists may supply alternatives without GP referral...

Expected resolution: 19 May 2022

Estradot® 75microgram patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradot®  75microgram patches (PDF:204KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 29 Apr 2021

Rivastigmine 4.6mg/24hours and 9.5mg/24hours transdermal patches

high DHSC MSN

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Estradiol (Estradot®) transdermal patches

medium DHSC MSN

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Fentanyl (Durogesic® DTrans®) patches

medium DHSC MSN

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Buprenorphine (Reletrans® ) 5micrograms/hour and 15micrograms/hour transdermal patches

medium DHSC MSN

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Buprenorphine (Relevtec®) 35micrograms/hour, 52.5micrograms/hour, 70micrograms/hour transdermal patches Buprenorphine (Bupeaze®) 52.5micrograms/hour transdermal patches

medium DHSC MSN

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Estradiol (Progynova® TS) 50micrograms/24hours and 100micrograms/24hours transdermal patches

medium DHSC MSN

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Oxybutynin (Kentera® ) 3.9mg/24hours transdermal patches

Medium DHSC MSN

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What to Do If Your Medication Is Affected

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Data sources: NHSBSA Serious Shortage Protocols · DHSC Medicine Supply Notifications · British Menopause Society
This page is automatically updated when new shortage data is published. Last checked: 8 February 2026.