Antidepressant Shortage UK

Track antidepressant medicine supply issues across the UK

Updated 8 February 2026 from official DHSC & NHS data
9
Active shortages
8
High severity
Antidepressant shortages can be particularly distressing as sudden interruption of these medications can cause withdrawal symptoms. Sertraline, the most prescribed antidepressant in the UK, and venlafaxine have both faced supply issues. We monitor all SSRI and SNRI shortages daily.

Current Active Shortages

Venlafaxine 37.5mg modified release tablet

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Venlafaxine 37.5mg modified release tablet (PDF:156KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 23 June 2025

Fluoxetine 40mg capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Fluoxetine 40mg capsules (PDF:139KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 29 Jan 2021

Fluoxetine 30mg capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Fluoxetine 30mg capsules (PDF:144KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 20 Oct 2020

Fluoxetine 40mg capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Fluoxetine 40mg capsules (PDF:135KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 20 May 2020

Fluoxetine 10mg tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Fluoxetine 10mg tablets (PDF:134KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 12 Mar 2020

Fluoxetine 40mg capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Fluoxetine 40mg capsules (PDF:131KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 3 Oct 2019

Fluoxetine 30mg capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Fluoxetine 30mg capsules (PDF:124KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 3 Oct 2019

Fluoxetine 10mg capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Fluoxetine 10mg capsules (PDF:151KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 3 Oct 2019

Venlafaxine 37.5mg modified-release tablets

medium DHSC MSN

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What to Do If Your Medication Is Affected

How MedWatch Helps

MedWatch monitors official UK government data sources daily, including DHSC Medicine Supply Notifications and NHSBSA Serious Shortage Protocols. We alert you before your pharmacy runs out — giving you time to plan ahead with your GP or pharmacist.

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Data sources: DHSC Medicine Supply Notifications · NHS England · MHRA
This page is automatically updated when new shortage data is published. Last checked: 8 February 2026.